- How native GLP-1 works
- GLP-1 impairment and T2D
- How Victoza® addressed incretin impairment in adults with T2D
Mechanism of Action
The Victoza® mechanism of action works in multiple systems1
Victoza® slows gastric emptying and the rate at which glucose enters the blood after meals.
Victoza® helps lower hepatic glucose output by suppressing pancreatic glucagon secretion.
Victoza® stimulates beta cells to release insulin when blood glucose is high.
- Victoza [package insert]. Plainsboro, NJ: Novo Nordisk Inc; August 2017.
- Marso SP, Daniels GH, Brown-Frandsen K, et al; the LEADER Steering Committee on behalf of the LEADER Trial Investigators. Liraglutide and cardiovascular outcomes in type 2 diabetes. N Engl J Med. 2016;375(4):311-322.